PEPTIDES 2019 #1 – The oncogenic lncRNA RP11-499F3.2 promotes tumorigenesis and cetuximab resistance via activation of Wnt2B signaling #10 – Optical biosensors that provide new insights into biomembrane-mediated events#100 – Development of polyglutamic acid/chitosan-based intranasal peptide nanovaccine#101 – Structural mechanisms of atypical conotoxin modulators of the nicotinic acetylcholine receptors#102 – Development and optimization of GLP-1 analogs with improved drug delivery characteristics through conjugation to other molecules using Copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) chemistry#103 – Liposomal Delivery System for Lipopeptide-based Vaccine against Group A Streptococcus Infection#104 – Synergy between sortase A inhibitors and antimicrobial peptides against antibiotic resistant bacteria#105 – A Computational study of the XLA peptide as an Akt-1 PH inhibitor#106 – Development of autophagy-inducing peptides as a potential therapy for motor neurone disease#107 – Synthesis and anti-tumour activity of a neoantigen peptide vaccine#108 – Macropinocytosis-inducing Peptide – Its Applications and Mechanism#109 – Bile acid-liposomes as a new delivery system for peptide-based vaccine against Group A Streptococcus#11 – Integrated omics for tissue-based mapping of the human proteome#110 – Pharmacokinetics and Biodistribution of HsTX1[R14A] in Mice#111 – Microinjection: An Approach for Assessing Cellular Toxicity of Peptide Modulators of Intracellular Protein-Protein Interactions#112 – Peptide Hydrogels for Pain#113 – Everything old is new again: the surprising utility of prodrugs for beyond rule-of-five compounds#114 – Tandem Domain Evasins: Inhibitors of Chemokine-mediated Inflammation#115 – Validation of Novel Modalities Targeting Protein: Protein Interactions using Mini-proteins #116 – Fmoc-Cys(Msbh) – a sophisticated building block for cysteine-rich peptides. A journey from discovery through to large scale production.#117 – Short arginine analogs: peptide synthesis and prediction of biological effects#118 – A peptide from Testudo horsfieldii tortoise spleen as a potential helper for reducing acute radiation syndrome.#119 – Native Chemical Ligation-Photodesulfurisation in Flow #12 – Accelerating DIA Using Fast Microflow LC Gradients for Large Scale Quantitative Proteomics#120 – An efficient strategy for N-terminal modification of unprotected peptides by utilizing hydrophilic protecting groups#121 – Combined administration of PTX and s-HM-3 in TPGS/solutol micelle system for oncotarget therapy#122 – Rationally Designed α-Conotoxin Analogues Maintained Analgesia Activity and Weakened Side Effects#123 – Functional Role of a Novel Long Noncoding RNA TTN-AS1 in Esophageal Squamous Cell Carcinoma Progression and Metastasis#124 – Efficient Semisynthesis of Glycosyl-interferon-β#125 – Protein regulation at atomic resolution: Exploring the effects of posttranslational modifications on HMGN1#126 – Exploring the sequence diversity of novel cyclotides from Vietnamese Viola species#127 – Structure-Activity Relationships of Miniaturised α-Conotoxins#128 – Downsizing promiscuous Bim BH3 domain into a potent, cell-permeable, selective inhibitor of oncogenic Bcl2A1 and Mcl-1 proteins#129 – Chemical synthesis of interferon gamma#13 – Ion mobility-mass spectrometry: An added dimension for structural biology in the context of protein aggregation#130 – Distinct structural and biological differences between the N- and C-terminal regions of granulins #131 – Synthesis of naturally occurring N-methylated cyclic tetrapeptides#132 – Genetically-encoded bicyclic architectures displayed on phage#133 – Synthesis of Thrombin Inhibitors Bearing Acid-Stable Sulfotyrosine Mimics#134 – Mechanism of the inhibitory interference in human antimicrobial peptides#135 – The widely used medicinal herbs Hybanthus enneaspermus F.Muell is rich in cyclotide with cytotoxic activity against cancer cell lines#136 – Synthesis of cyclic peptide inhibitors of FXIIa as novel anticoagulants#137 – Development of novel self-adjuvanting peptide-based subunit vaccine against herpes simplex virus-2#138 – Plasticity of PDZ-dependent PSD-95 interactions#139 – Towards Cell-permeable Macrocycles using mRNA Display#14 – New Cryo-EM methods present exciting challenges for the ‘Omics communities #140 – Development an oral based delivery system for peptide vaccine against Group A Streptococcus (GAS).#141 – Optimization of a CXCR4 receptor mimetic peptide#142 – The Development of Linear and Cyclic Lipopeptide based Adjuvants#143 – Precisely controlled intracellular trafficking and enhanced gene silencing of nucleic acid-peptide conjugates.#144 – Structure and function of O-GlcNAc/phosphorylation cross talk in Tau protein#145 – Novel analogues of Fengycin A with enhanced chemical stability#146 – The design and development of a potent and selective C5aR1 agonist#147 – Development of novel diketopiperazines as eco-friendly antifouling biocides#148 – Structural parameters modulating the cellular uptake of a macrocyclic peptide from the common zinnia #149 – Controlling the assembly of D/L cyclic peptides through a linear scaffold#15 – Customizing macromolecules through chemical ligation #150 – A novel approach to quantify oxytocin in biological samples via mass spectrometry#151 – Chemical biology tools for the characterisation and the exploitation of antibiotic biosynthetic pathways#152 – Exploiting the p21 template: Development of a broad-spectrum cancer diagnostic and peptidomimetic therapeutic with defined 310-helical structure#153 – Glycopeptide vaccine based on DNA Supramolecular Hydrogels#154 – Astratides: Insight into bioactive compounds in Chinese Medicine from Astragalus membranaceus #155 – Synthesis of Nanobody80 using SPPS#156 – Polyacrylate-peptide liposomal formulation as a therapeutic vaccine candidate against cervical cancer#157 – Cell penetrating peptides to increase membrane permeability of larger cyclic peptides as inhibitors for protein-protein interactions #158 – Fast peptide-MHC docking based with 3D Convolutional Neural Net#159 – A ready-to-read on-bead peptide sequencing method using two-dimensional SERS encoders #16 – Targeting Sodium Channels for the Treatment of Pain#160 – Chemcial synthesis of ubiquitinated histones for biochemical and structural analysis#161 – Transcriptomic-Proteomic Correlation in the Predation-Evoked Venom of the Cone Snail, Conus imperialis#162 – Applications of cyclotides in the pharmaceutical and agricultural industries#163 – Reconstitution of non-ribosomal peptide synthesis in vitro: the story of teicoplanin biosynthesis#164 – Unravelling the diversity and distribution of insect antimicrobial peptides#165 – Synthesis and application of advanced fluorescent probes #166 – Detection of bioactive peptides including gonadotrophin-releasing factors (GnRHs) in horse urine using ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS)#167 – Photooxidation of oxazoles – a new approach to solid-phase peptide synthesis#168 – Development of novel relaxin-3 analogues for blood-brain barrier penetration#169 – Phosphorylation of α-synuclein induces distinct strains and propagation properties#17 – Development of granulin derived peptides as wound healing agents #170 – Dichloroacetone – A robust approach to acetone-linked bicyclic dimer peptides#171 – Synthesis of Peptide Natural Products Enabled by New Strategies for Late-Stage Modification#173 – Insulin fatty acid acylation scan: Discovery of Insulin 327, an acylated hepato-preferential insulin analogue with high insulin receptor affinity#174 – Robust methodology for assembling peptides with tryptophan C-mannosylation#175 – Peptide modulating tension in cell membranes: the regulation of cell movement and morphology via actin remodeling#177 – Tyrosine sulfation is an important post-translational modification in anti-inflammatory peptides from blood-feeding organisms.#178 – The New Kid On The Block: Discovery and development of NaV channel inhibitor and µ-conotoxin NgIIIA#179 – Peptide cyclisation using a pyridine-2,6-dicarbonitrile linker#18 – Validating the relaxin-3 neuropeptide receptor, RXFP3, as a promising target for the treatment of obesity and depression #180 – Structure-activity study of the analgesic NaV1.7 inhibiting venom peptide Pn3a#181 – Chemical strategies to tune potency, selectivity and stability of neuropeptides#182 – Design and synthesis of a PD-1 binding peptide and evaluation of its anti-tumor activity#183 – A Zn(II)-catalyst permits bis-thioether peptide stapling under non-basic conditions#184 – Noncanonical peptides as probes and inhibitors for flavivirus proteases#185 – Identification and Optimisation of a Lead Bromodomain Inhibitor#186 – Membrane-bound structure and membrane selectivity of cationic antimicrobial peptide Hymenochirin-1Pa and its D9K analog #187 – Evaluation of biological activity of frog skin-derived peptide, ranatensin#188 – Thiol-cyanobenzothiazole ligation: an efficient preparation of peptide-oligonucleotide conjugates#189 – The Structural Features of an Ancient Peptide Family Buried within Vicilin Precursors.#19 – A synthetic glycolipid peptide vaccine for malaria#190 – Cyclic peptide conjugates: their mode-of action and interaction with cell membranes#192 – Cyclic peptides to probe the internal interactome of PDZ domains#193 – Decoding the complex regulation of cone snail venoms: connecting evolution and drug discovery#194 – Novel methods for inhibiting amyloidogenesis in the presence of peptides in order to block hydrophobic interaction#195 – Cytosolic Delivery of Macromolecules by Endosomolytic Cationic Helical Peptide#196 – Exploring the oxytocin receptor as a novel target for breast cancer#197 – Affinity-based functionalization of biomedical polymeric micelles through polymer-binding peptides#198 – Backbone cyclization of native α-conotoxin CIA: Influences on structure and bioactivity#199 – The use of peptide-membrane interactions in the design of selective and potent sodium channel inhibitors #2 – Mediator Lipidomics: Towards Comprehensive Metabolic Profiling of Eicosanoids and Related Fatty Acids#20 – Rapid screening of cyclotide-based libraries for the selection of potent E3 ligase antagonists #200 – Discovery of tight binding inhibitors of hip1 a mycobacterium tuberculosis drug target#203 – Tripeptide-induced mechanical property modulation of mesenchymal stem cells stimulates proliferation and wound healing#204 – Enhancing activity by combining antimicrobial peptides and antibiotics#205 – Evolving Peptide G Protein-Coupled Receptors (GPCRs) to Facilitate Structural Studies Using a Novel Lentiviral Based Method of Directed Evolution#206 – Peptide based hydrogen sulfide responsive nanostructures for biomedical applications#207 – Analysis of granulin peptide folding #208 – Synthesis and biological activity of celogentin analogues#209 – Iterative optimization of the cyclic peptide SFTI-1 yields potent inhibitors of neutrophil proteinase 3#21 – Highly specific biochips for early diagnosis in search of Eldorado#210 – Taking active steps to improving the pharmacokinetics of disulfide-rich peptides#211 – μ‐Conotoxin KIIIA isomer selectivity on human voltage gated sodium channels#212 – Enzymatic ligation of Nav1.7-inhibiting gating modifier and pore blocker toxins#213 – Exploration of amyloidogenic core β-sheet and the FEL-mediated dissociation of amyloid fibrils in SAA#214 – The characterization of triglyceride-based nanodroplets and their interaction with lipid specific peptides and proteins#215 – A fluorescent protein-tagged peptide toxin as a tool for KV1.3 visualisation #216 – Combinatorial peptide libraries in venoms of Australian nettle caterpillars #217 – From sunflower to skin cancer: Development of melanocortin receptor-1 agonists based on the cyclic peptide framework of sunflower trypsin inhibitor-1#218 – Development of a lentiviral nanobody screening platform against peptide GPCRs#219 – Delivery of a peptide-based vaccine against Group A Streptococcus with the help of cell penetrating peptides#22 – Glycopeptide Vaccines For Cancer Immunotherapy#220 – Anchoring epitopes to improve grafted peptide structure and activity#221 – A*STAR Peptide Engineering Platform (PEP): Targeting Macrocyclic Modalities for Protein-Protein Interactions#222 – In-cell structure determination of an antimicrobial peptide by DNP solid-state NMR#224 – Receptor-Mediated MAPK and Akt Signaling are Maintained in Gamma-Irradiated FroZen Cells#225 – Synthesis and Evaluation of a Library of Self-Adjuvanting Peptide and Protein Vaccines against Mycobacterium tuberculosis #226 – Development of a single-chain peptide agonist for the G-protein-coupled receptor, RXFP1#227 – Improving in vivo analgesia through glycosylation of bilorphin, a biased μ-opioid derived from a novel tetrapeptide class found in an Australian fungus #24 – Enhancing or manipulating oxidative protein folding by selenium chemistry #25 – Stabilising peptoid helices using fluorinated monomers#26 – A platform for in-solution enrichment from large libraries to identify peptide inhibitors of protein-protein interactions#27 – Peptide synthesis by peptide synthetases #28 – Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics#29 – Penicillin-binding protein-type thioesterases; scope, limitation and its application#3 – Reforming the Regulatory Environment for Innovative Health Technologies: Identifying Congestion and Filling Gaps#30 – Synthesis and identification of auto-inducing thiodepsipeptides#31 – Utilizing Peptidic-Tools to Investigate Cell-Cell Communication in Bacteria#32 – Mechanisms of nonribosomal peptide diversification #33 – Evasins: Tick Salivary Proteins that Inhibit Mammalian Chemokines #34 – A Disulfide-scan of Insulin by [3+1] Methodology Exhibits Site-specific Influence on Bioactivity #35 – Understanding signaling bias at the insulin receptor. #36 – Structural venomics: evolution of a complex chemical arsenal by massive duplication and neofunctionalization of a single ancestral fold#37 – NMR and EPR spectroscopy of proteins and peptides with genetically encoded unnatural amino acids#38 – Peptide-based surface-fill hydrogel facilitates miRNA delivery to treat mesothelioma#39 – Peptide nanotubes as synthetic miniproteins#4 – Patentomics: personalised protection#40 – Efficacy of antimicrobial peptoids against Staphylococcus aureus biofilms, and in vivo to treat abrasion wounds infected with Pan-resistant Klebsiella pneumonia#41 – Brain extracellular-matrix mimicking peptide hydrogels for long-term support of primary neurons#42 – PNA-Encoded Molecules to Program Assemblies and Reactions #43 – Using cryo-EM to understand peptide GPCR structure function #44 – Understanding allosteric modulation of GPCRs through structural biology #45 – Crosslinking furan-modified peptides for GPCR target identification on live cells #46 – Animal toxins and GPCRs, a promising combination for science and medicine#47 – Activation of the relaxin receptor RXFP1 is by a tethered agonist#48 – Studying the molecular pharmacology of peptide- and protein-activated receptors#49 – Peptide-Based Therapeutics: Paving the Way from the Lab to the Clinic#5 – When metalloproteins go rogue: application of metalloproteomics to understand Neurodegeneration#50 – A synthetic platform for the generation of anticoagulant sulfoproteins libraries #51 – Design and Synthesis of 13-membered Cyclic Tetrapeptides as Novel Antimicrobials with Enhanced Therapeutic Window #52 – Biased Inteleukin-1 Receptor Allosteric Modulation with Lactam Peptides for Mitigating Inflammation without Compromising Immuno-Vigilance#53 – Semi-synthesis of Homogeneous Glycoproteins #54 – Tools and methods for probing the biology of tryptophan C-mannosylation #55 – Discovery and biosynthesis of ribosomally synthesized and posttranslationally modified peptides (RiPPs)#56 – Optical control of protein domain conformation and cell signaling #57 – Chemoselective tyrosine bioconjugation of peptides and proteins through sulfate Click reaction#58 – CXMS Analysis for Complex Protein Structures and Protein-Protein Interactions #59 – Data Reduction and Visualization Technologies for the Design & Optimization of Therapeutic Peptides #6 – ProCan®: from cancer tissue proteomics to clinical application.#60 – An intellectual property perspective for industry and academic partnerships#61 – Peptide therapeutics for metabolic disorders #62 – Application of diselenide-selenoester ligation towards the synthesis of phosphorylated IGFBP-2 #63 – Deadly cures: venom-peptide inhibitors of acid-sensing ion channel 1a for treating ischemic injuries of the heart and brain #64 – Gate2Brain, Opening the Gate to CNS#65 – Biomembrane plasticity and its role in membrane damage, recovery and repair#66 – Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.#67 – Pain-causing peptides from ant venoms#68 – The power of chemoselectivity: Functional protein-conjugates for intra- and extracellular targeting #69 – Navigating the sequence space of Bcl-2-binding peptides #7 – Towards liquid biopsy screening for esophageal adenocarcinoma#71 – Affibody-based next-generation therapeutics #72 – Challenging olefin metathesis with peptidomimetic synthesis#73 – A Systematic Approach to Targeting Protein Surfaces#74 – Sugars & proteins: towards a synthetic biology#75 – Venoms to drugs #8 – Alzheimer’s Disease – an Assay Odyssey#9 – Examples of how a novel surface chemistry enables gold surface biosensors to carry out selective early diagnosis: In search of Eldorado #99 – China Peptide Bank